We are also one of the leading sarcoma specialists.

What is Leukemia?

Leukemia begins in the bone marrow and is characterized by the overproduction of abnormal white blood cells that can't function properly and crowd out healthy cells in the bloodstream. This weakens your body’s ability to fight infection, carry oxygen, and control bleeding.

Though leukemia can affect people of all ages, it is more common in adults, particularly men. An unusually high white blood cell count doesn’t always mean leukemia, but persistent elevation requires further investigation to determine the underlying cause.

Types of Leukemia We Treat

We specialize in chronic leukemias, which often progress more slowly than acute forms.

Chronic Lymphocytic Leukemia (CLL)

It is the most common type of leukemia in adults over 50. Progresses gradually and requires ongoing monitoring and expert management.

Chronic Myelogenous Leukemia (CML)

CML is caused by genetic mutations in bone marrow cells. It typically progresses slowly in its early stages but can become more aggressive without treatment.

Symptoms of Leukemia

Chronic leukemias may develop slowly, but possible signs can include:

  • Fatigue, weakness, or anemia
  • Persistent infections
  • Enlarged lymph nodes or spleen
  • Easy bruising or bleeding
  • Night sweats or fevers
  • Unexplained weight loss

What is Lymphoma?

Lymphoma begins in the lymphatic system, part of your body’s immune defense.  Cancerous lymphocytes (a type of white blood cell) multiply and collect in lymph nodes, spleen, or bone marrow, interfering with immune function.

Types of Lymphoma We Treat

We focus on non-Hodgkin lymphomas (NHL), which are more common than Hodgkin’s lymphoma and include many subtypes.

Indolent (slow-growing) NHL

Progresses gradually, sometimes with few symptoms at first. Monitoring may be recommended until treatment becomes necessary.

Aggressive (fast-growing) NHL

Spreads quickly and requires urgent treatment with chemotherapy, targeted therapy, or immunotherapy.

Symptoms of Lymphoma

The most common early sign of lymphoma is the painless swelling of lymph nodes in the neck, armpit, or groin. Other symptoms may include:

  • Fevers and drenching night sweats
  • Unexplained weight loss
  • Fatigue or persistent weakness
  • Shortness of breath or cough from pressure on the chest
  • Abdominal pain or swelling from enlarged lymph nodes or spleen

What Makes Our Care Different for Leukemia & Lymphoma

At the Cancer Center of Southern California, you benefit from the leadership of Dr. Sant P. Chawla, a globally recognized oncologist trained at MD Anderson and former head of the cancer program at Cedars-Sinai. With more than 30 years of research and clinical trial experience, Dr. Chawla and our team of specialists bring world-class expertise and customized care plans to every patient we treat.

  • Collaborative Care: Our oncologists collaborate with hematologists, pathologists, and other specialists to ensure your treatment is both comprehensive and precise.
  • Leaders in Clinical Trials: We are often among the top enrollers in national studies, giving you access to tomorrow’s treatments today.
  • Second Opinions: We carefully review your records to confirm your diagnosis and provide alternative treatment strategies when other options seem limited.
  • Fast Appointments: Unlike large hospital systems, where you may wait months, we see most new patients within days or weeks.
  • Financial Accessibility: We welcome patients with HMO and Kaiser insurance and assist with financial support programs, including finding sponsorship for trial-related costs, such as travel and lodging, when available.

Diagnosis of Leukemia & Lymphoma

At the Cancer Center of Southern California, our focus is on confirming the subtype, stage, and genetic profile of the cancer so we can match you with the most effective treatment.

Our evaluation may include:

  • Pathology review of biopsy and blood results to confirm accuracy
  • Molecular and genetic testing to identify mutations that guide targeted therapy
  • Imaging studies (PET, CT, MRI) to assess disease spread

This advanced diagnostic review ensures that your care plan is guided by the latest and most precise information. Based on our assessment, we may identify new treatment options, provide a trusted second opinion, determine your eligibility for clinical trials, or recommend personalized approaches tailored to your specific condition.

Treatment of Leukemia & Lymphoma

At the Cancer Center of Southern California, we believe treatment should be personal, precise, and compassionate. Guided by Dr. Chawla’s decades of research leadership, our team designs care plans based on your cancer type, stage, genetic profile, and overall health.

We may combine established treatments with newer approaches, including:

  • Chemotherapy for many types of lymphoma and select leukemias
  • Targeted therapy that blocks genetic drivers of cancer growth
  • Immunotherapy to help your immune system recognize and fight cancer
  • Stem cell transplant in select cases, to restore healthy marrow and blood production
  • Radiation therapy for certain localized lymphomas
  • Clinical trials, which offer access to promising investigational drugs

Frequently Asked Questions

What types of leukemia and lymphoma do you treat?

We specialize in chronic leukemias (CLL, CML) and most forms of non-Hodgkin lymphoma (NHL). If you’re unsure about your type of blood cancer, our team can review your records and confirm your diagnosis.

Why would I need a second opinion for leukemia or lymphoma?

Blood cancers are complex, and treatment can vary based on the exact subtype and genetic profile. A second opinion with our experts can help confirm your diagnosis and inform you about all available treatment options, including advanced therapies and clinical trials.

Are clinical trials available for leukemia and lymphoma?

Yes! We are often among the top enrollers in national studies, giving our patients access to promising investigational therapies. Participation in a trial may offer new options if standard treatments are not effective for your cancer.

2811 Wilshire Blvd #414
Santa Monica, CA 90403

Phone: 310-552-9999

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